Tanshinone IIA prevents platelet activation and down-regulates CD36 and MKK4/JNK2 signaling pathway

Tanshinone IIA prevents platelet activation and down-regulates CD36 and MKK4/JNK2 signaling pathway

Abstract Background Tanshinone IIA (TS IIA), a multi-pharmaceutical compound from traditional Chinese herb, is effective for treatment of atherothrombosis. However, the underlying mechanisms of TS IIA-mediated anti-platelet activation effect are still poorly understood. As shown in our previous stud...

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Bibliographic Details
Main Authors: Hua Wang, Lin Zhong, Shaohua Mi, Nianpeng Song, Wei Zhang, Ming Zhong
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Cardiovascular Disorders
Subjects:
Tanshinone IIA
Platelet activaton
CD36
Atherothrombosis
Online Access:https://doi.org/10.1186/s12872-019-01289-z

Internet

https://doi.org/10.1186/s12872-019-01289-z

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