Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner.

The contribution of natural killer (NK) cells to the treatment efficacy of dendritic cell (DC)-based cancer vaccines is being increasingly recognized. Much current efforts to optimize this form of immunotherapy are therefore geared towards harnessing the NK cell-stimulatory ability of DCs. In this s...

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Bibliographic Details
Main Authors: Sébastien Anguille, Heleen H Van Acker, Johan Van den Bergh, Yannick Willemen, Herman Goossens, Viggo F Van Tendeloo, Evelien L Smits, Zwi N Berneman, Eva Lion
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0123340