Type I Interferons Direct Gammaherpesvirus Host Colonization.

Type I Interferons Direct Gammaherpesvirus Host Colonization.

Gamma-herpesviruses colonise lymphocytes. Murid Herpesvirus-4 (MuHV-4) infects B cells via epithelial to myeloid to lymphoid transfer. This indirect route entails exposure to host defences, and type I interferons (IFN-I) limit infection while viral evasion promotes it. To understand how IFN-I and it...

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Bibliographic Details
Main Authors: Cindy S E Tan, Clara Lawler, Janet S May, Gabrielle T Belz, Philip G Stevenson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005654

Internet

https://doi.org/10.1371/journal.ppat.1005654

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