Development of an epidermal growth factor derivative with EGFR blocking activity.

The members of the epidermal growth factor (EGF)/ErbB family are prime targets for cancer therapy. However, the therapeutic efficiency of the existing anti-ErbB agents is limited. Thus, identifying new molecules that inactivate the ErbB receptors through novel strategies is an important goal on canc...

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Bibliographic Details
Main Authors: Clara Panosa, Francesc Tebar, Montserrat Ferrer-Batallé, Humphrey Fonge, Masaharu Seno, Raymond M Reilly, Anna Massaguer, Rafael De Llorens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3728333?pdf=render