Identification of hub genes associated with RNAi-induced silencing of XIAP through targeted proteomics approach in MCF7 cells

Identification of hub genes associated with RNAi-induced silencing of XIAP through targeted proteomics approach in MCF7 cells

Abstract Background The X-linked inhibitor of apoptosis protein (XIAP) is the most potent caspase inhibitor of the IAP family in apoptosis pathway. This study aims to identify the molecular targets of XIAP in human breast cancer cells exposed to XIAP siRNA by proteomics screening. The expression of...

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Bibliographic Details
Main Authors: Mehdi Agha Gholizadeh, Fatemeh T. Shamsabadi, Ahad Yamchi, Masoud Golalipour, Gagan Deep Jhingan, Majid Shahbazi
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cell & Bioscience
Subjects:
Breast cancer
XIAP
RNA interference
Apoptosis
Molecular targets
Proteomics
Online Access:http://link.springer.com/article/10.1186/s13578-020-00437-9

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http://link.springer.com/article/10.1186/s13578-020-00437-9

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