The Copper(II)-Assisted Connection between NGF and BDNF by Means of Nerve Growth Factor-Mimicking Short Peptides

The Copper(II)-Assisted Connection between NGF and BDNF by Means of Nerve Growth Factor-Mimicking Short Peptides

Nerve growth factor (NGF) is a protein necessary for development and maintenance of the sympathetic and sensory nervous systems. We have previously shown that the NGF N-terminus peptide NGF(1-14) is sufficient to activate TrkA signaling pathways essential for neuronal survival and to induce an incre...

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Bibliographic Details
Main Authors: Irina Naletova, Cristina Satriano, Adriana Pietropaolo, Fiorenza Gianì, Giuseppe Pandini, Viviana Triaca, Giuseppina Amadoro, Valentina Latina, Pietro Calissano, Alessio Travaglia, Vincenzo Giuseppe Nicoletti, Diego La Mendola, Enrico Rizzarelli
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
neurotrophin
metal ions
copper
TrK
p75
CREB
synapsin
Alzheimer’s disease
nerve growth factor
brain derived neurotrophic factor
Online Access:https://www.mdpi.com/2073-4409/8/4/301

Internet

https://www.mdpi.com/2073-4409/8/4/301

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