IL17 factors are early regulators in the gut epithelium during inflammatory response to Vibrio in the sea urchin larva

IL17 cytokines are central mediators of mammalian immunity. In vertebrates, these factors derive from diverse cellular sources. Sea urchins share a molecular heritage with chordates that includes the IL17 system. Here, we characterize the role of epithelial expression of IL17 in the larval gut-assoc...

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Bibliographic Details
Main Authors: Katherine M Buckley, Eric Chun Hei Ho, Taku Hibino, Catherine S Schrankel, Nicholas W Schuh, Guizhi Wang, Jonathan P Rast
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/23481