Cytochrome P450-epoxygenated fatty acids inhibit Müller glial inflammation

Abstract Free fatty acid dysregulation in diabetics may elicit the release of inflammatory cytokines from Müller cells (MC), promoting the onset and progression of diabetic retinopathy (DR). Palmitic acid (PA) is elevated in the sera of diabetics and stimulates the production of the DR-relevant cyto...

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Bibliographic Details
Main Authors: Cayla D. Ontko, Megan E. Capozzi, Minjae J. Kim, Gary W. McCollum, John S. Penn
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89000-1