Oleanolic Acid Improves Obesity-Related Inflammation and Insulin Resistance by Regulating Macrophages Activation

Oleanolic Acid Improves Obesity-Related Inflammation and Insulin Resistance by Regulating Macrophages Activation

The chronic low-grade inflammation of adipose tissues, primarily mediated by adipose tissue macrophages (ATMs), is the key pathogenic link between obesity and metabolic disorders. Oleanolic acid (OA) is a natural triterpenoid possessing anti-diabetic and anti-inflammation effects, but the machinery...

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Bibliographic Details
Main Authors: Wanqing Li, Hongxiang Zeng, Min Xu, Chenglong Huang, Linfen Tao, Jun Li, Ting Zhang, Hong Chen, Jing Xia, Chunli Li, Xi Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
oleanolic acid
obesity
inflammation
macrophages
ROS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.697483/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.697483/full

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