Pharmacokinetic / pharmacodynamic relationships of liposomal amphotericin B and miltefosine in experimental visceral leishmaniasis.

<h4>Background</h4>There is a continued need to develop effective and safe treatments for visceral leishmaniasis (VL). Preclinical studies on pharmacokinetics and pharmacodynamics of anti-infective agents, such as anti-bacterials and anti-fungals, have provided valuable information in th...

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Bibliographic Details
Main Authors: Andrew A Voak, Andy Harris, Jose Miguel Coteron-Lopez, Iñigo Angulo-Barturen, Santiago Ferrer-Bazaga, Simon L Croft, Karin Seifert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009013