Crocin alleviates schizophrenia-like symptoms in rats by upregulating silent information regulator-1 and brain derived neurotrophic factor

Background: In neonatal rats, MK-801 treatments can produce schizophrenia-like symptoms. Crocin is a water soluble carotenoid in Saffron that exerts potent neuroprotective effects. This work aimed to demonstrate the function of crocin in the alleviation of motor and cognitive impairments elicited by...

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Bibliographic Details
Main Authors: Xi-juan Sun, Xin Zhao, Jun-ning Xie, Hao Wan
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Comprehensive Psychiatry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0010440X20300511