S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis.

S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis.

Neutrophils are essentially involved in protective immune responses against invading infective larvae of filarial nematodes. The present study investigated the impact of S100A8/S100A9 on protective immune responses against the rodent filarial nematode Litomosoides sigmodontis. S100A9 forms with S100...

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Bibliographic Details
Main Authors: Stefan J Frohberger, Frederic Fercoq, Anna-Lena Neumann, Jayagopi Surendar, Wiebke Stamminger, Alexandra Ehrens, Indulekha Karunakaran, Estelle Remion, Thomas Vogl, Achim Hoerauf, Coralie Martin, Marc P Hübner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008119

Internet

https://doi.org/10.1371/journal.pntd.0008119

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