Neuronal reprograming of protein homeostasis by calcium-dependent regulation of the heat shock response.

Protein quality control requires constant surveillance to prevent misfolding, aggregation, and loss of cellular function. There is increasing evidence in metazoans that communication between cells has an important role to ensure organismal health and to prevent stressed cells and tissues from compro...

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Bibliographic Details
Main Authors: M Catarina Silva, Margarida D Amaral, Richard I Morimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3757039?pdf=render