A diverse repertoire of CD4 T cells targets the immediate-early 1 protein of human cytomegalovirus
T cell responses to the immediate-early 1 (IE-1) protein of human cytomegalovirus (HCMV) are associated with protection from viral disease. Thus, IE-1 is a promising target for immunotherapy. CD8 T cell responses to IE-1 are generally strong. In contrast, CD4 T cell responses to IE-1 were described...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-11-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00598/full |