A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy

A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy

Abstract Metastasis is the primary cause of cancer-related mortality in colorectal cancer (CRC) patients. How to improve therapeutic options for patients with metastatic CRC is the core question for CRC treatment. However, the complexity and diversity of stromal context of the tumor microenvironment...

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Bibliographic Details
Main Authors: Li-Heng Che, Jing-Wen Liu, Jian-Ping Huo, Rong Luo, Rui-Ming Xu, Cai He, Yu-Qing Li, Ai-Jun Zhou, Piao Huang, Yong-Yu Chen, Wen Ni, Yun-Xia Zhou, Yuan-Yuan Liu, Hui-Yan Li, Rong Zhou, Hui Mo, Jian-Ming Li
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-021-00312-y

Internet

https://doi.org/10.1038/s41421-021-00312-y

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