A Novel Urine Exosomal lncRNA Assay to Improve the Detection of Prostate Cancer at Initial Biopsy: A Retrospective Multicenter Diagnostic Feasibility Study

A Novel Urine Exosomal lncRNA Assay to Improve the Detection of Prostate Cancer at Initial Biopsy: A Retrospective Multicenter Diagnostic Feasibility Study

Purpose: This study aimed at developing and validating a novel noninvasive urinary exosome-based post-DRE (digital rectal examination) lncRNA assay to diagnose PCa (prostate cancer) and clinically significant PCa (Gleason score ≥ 7) from the initial prostate biopsy. Methods: A total of 602 urine sam...

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Bibliographic Details
Main Authors: Yun Li, Jin Ji, Ji Lyu, Xin Jin, Xing He, Shaojia Mo, Huan Xu, Jingyi He, Zhi Cao, Xi Chen, Yalong Xu, Lei Wang, Fubo Wang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
exosomes
prostate cancer
lncRNA assay
PCA3
MALAT1
diagnosis
Online Access:https://www.mdpi.com/2072-6694/13/16/4075

Internet

https://www.mdpi.com/2072-6694/13/16/4075

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