A Gammaherpesvirus MicroRNA Targets EWSR1 (Ewing Sarcoma Breakpoint Region 1) In Vivo To Promote Latent Infection of Germinal Center B Cells

A Gammaherpesvirus MicroRNA Targets EWSR1 (Ewing Sarcoma Breakpoint Region 1) In Vivo To Promote Latent Infection of Germinal Center B Cells

Gammaherpesviruses, including the human pathogens Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV), directly contribute to the genesis of multiple types of malignancies. In vivo, these viruses infect B cells and manipulate B cell biology to establish lifelong infectio...

Full description

Bibliographic Details
Main Authors: Yiping Wang, Emily R. Feldman, Whitney L. Bullard, Scott A. Tibbetts
Format: Article
Language:English
Published: American Society for Microbiology 2019-07-01
Series:mBio
Subjects:
ewsr1
mhv68
gammaherpesvirus
in vivo
mirna
Online Access:https://doi.org/10.1128/mBio.00996-19

Internet

https://doi.org/10.1128/mBio.00996-19

Similar Items