The role of ESCO2, SALL4 and TBX5 genes in the susceptibility to thalidomide teratogenesis
Abstract Thalidomide is widely used for several diseases; however, it causes malformations in embryos exposed during pregnancy. The complete understanding of the mechanisms by which thalidomide affects the embryo development has not yet been obtained. The phenotypic similarity makes TE a phenocopy o...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-47739-8 |