Identification of Novel Single-Nucleotide Variants With Potential of Mediating Malfunction of MicroRNA in Congenital Heart Disease

Identification of Novel Single-Nucleotide Variants With Potential of Mediating Malfunction of MicroRNA in Congenital Heart Disease

Congenital heart defects (CHDs) represent the most common human birth defects. Our previous study indicates that the malfunction of microRNAs (miRNAs) in cardiac neural crest cells (NCCs), which contribute to the development of the heart and the connected great vessels, is likely linked to the patho...

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Bibliographic Details
Main Authors: Wangkai Liu, Liangping Cheng, Ken Chen, Jialing Wu, Rui Peng, Yan-Lai Tang, Jinghai Chen, Yuedong Yang, Peiqiang Li, Zhan-Peng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
neural crest cells
single nucleotide variant
congenital heart defect
microRNA
post-transcriptional regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.739598/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.739598/full

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