Distinct contributions of Orai1 and TRPC1 to agonist-induced [Ca(2+)](i) signals determine specificity of Ca(2+)-dependent gene expression.
Regulation of critical cellular functions, including Ca(2+)-dependent gene expression, is determined by the temporal and spatial aspects of agonist-induced Ca(2+) signals. Stimulation of cells with physiological concentrations of agonists trigger increases [Ca(2+)](i) due to intracellular Ca(2+) rel...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3480383?pdf=render |