EGFR-IL-6 Signaling Axis Mediated the Inhibitory Effect of Methylseleninic Acid on Esophageal Squamous Cell Carcinoma

Epidemiological and experimental evidence indicate that selenium is associated with a reduced risk of some cancers, including esophageal cancer. However, the exact mechanism is still unclear. In the present study, we used esophageal squamous cell carcinoma (ESCC) cell lines and animal models to expl...

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Bibliographic Details
Main Authors: Yu Wang, Xianghe Liu, Guanghui Hu, Chenfei Hu, Yang Gao, Miaomiao Huo, Hongxia Zhu, Mei Liu, Ningzhi Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
MSA
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.719785/full