Neutralizing Anti-Rituximab Antibodies and Relapse in Membranous Nephropathy Treated With Rituximab

Neutralizing Anti-Rituximab Antibodies and Relapse in Membranous Nephropathy Treated With Rituximab

Membranous Nephropathy (MN) is an autoimmune disease associated with antibodies against podocyte proteins: M-type phospholipase A2 receptor (PLA2R1) or thrombospondin type-1 domain-containing 7A (THSD7A) in 70 and 3% of patients, respectively. Antibody titer is correlated with disease activity: risi...

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Bibliographic Details
Main Authors: Sonia Boyer-Suavet, Marine Andreani, Maël Lateb, Benjamin Savenkoff, Vesna Brglez, Sylvia Benzaken, Ghislaine Bernard, Patrick H. Nachman, Vincent Esnault, Barbara Seitz-Polski
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
membranous nephropathy
rituximab
anti-CD20 monoclonal antibody
immunogenicity
immuno-monitoring
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03069/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.03069/full

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