Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissueResearch in context

Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissueResearch in context

Background: The pharmacological activation of thermogenesis in brown adipose tissue has long been considered promising strategies to treat obesity. However, identification of safe and effective agents remains a challenge. In this study, we addressed this challenge by developing a cellular system wit...

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Bibliographic Details
Main Authors: Yan Qiu, Yingmin Sun, Danqing Xu, Yuanyuan Yang, Xiaojian Liu, Yuda Wei, Yanhao Chen, Zhuanghui Feng, Shuang Li, Md. Reyad-ul Ferdous, Yongxu Zhao, Hongxi Xu, Yuanzhi Lao, Qiurong Ding
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418304304

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http://www.sciencedirect.com/science/article/pii/S2352396418304304

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