Structural properties of MHC class II ligands, implications for the prediction of MHC class II epitopes.
Major Histocompatibility class II (MHC-II) molecules sample peptides from the extracellular space allowing the immune system to detect the presence of foreign microbes from this compartment. Prediction of MHC class II ligands is complicated by the open binding cleft of the MHC class II molecule, all...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-12-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3012731?pdf=render |