Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients

Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients

Summary: To fully decipher the immunogenicity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike protein, it is essential to assess which part is highly immunogenic in a systematic way. We generate a linear epitope landscape of the Spike protein by analyzing the serum immunogl...

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Bibliographic Details
Main Authors: Yang Li, Ming-liang Ma, Qing Lei, Feng Wang, Wei Hong, Dan-yun Lai, Hongyan Hou, Zhao-wei Xu, Bo Zhang, Hong Chen, Caizheng Yu, Jun-biao Xue, Yun-xiao Zheng, Xue-ning Wang, He-wei Jiang, Hai-nan Zhang, Huan Qi, Shu-juan Guo, Yandi Zhang, Xiaosong Lin, Zongjie Yao, Jiaoxiang Wu, Huiming Sheng, Yanan Zhang, Hongping Wei, Ziyong Sun, Xionglin Fan, Sheng-ce Tao
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Cell Reports
Subjects:
COVID-19
SARS-CoV-2
Spike protein
linear epitope landscape
neutralizing antibodies
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721002291

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http://www.sciencedirect.com/science/article/pii/S2211124721002291

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