5-Hydroxytryptophan Attenuates Somatic Signs of Nicotine Withdrawal

Abstract.: Abrupt nicotine cessation after chronic use disrupts monoaminergic systems and causes withdrawal signs/symptoms. In this study, the precursor of serotonin 5-hydroxytryptophan (5-HTP) relieved nicotine withdrawal signs. (−)-Nicotine bitartrate or equimolar sodium tartrate was infused into...

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Bibliographic Details
Main Authors: Yu Ohmura, Emily M. Jutkiewicz, Mitsuhiro Yoshioka, Edward F. Domino
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319306449