Late Passage Human Fibroblasts Induced to Pluripotency Are Capable of Directed Neuronal Differentiation

It is possible to generate induced pluripotent stem (iPS) cells from mouse and human somatic cells by ectopic expression of defined sets of transcription factors. However, the recommendation that somatic cells should be utilized at early passages for induced reprogramming limits their therapeutic ap...

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Bibliographic Details
Main Authors: Jun Liu, Huseyin Sumer, Jessie Leung, Kyle Upton, Mirella Dottori, Alice Pébay, Paul J. Verma
Format: Article
Language:English
Published: SAGE Publishing 2011-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368910X514305