Late Passage Human Fibroblasts Induced to Pluripotency Are Capable of Directed Neuronal Differentiation
It is possible to generate induced pluripotent stem (iPS) cells from mouse and human somatic cells by ectopic expression of defined sets of transcription factors. However, the recommendation that somatic cells should be utilized at early passages for induced reprogramming limits their therapeutic ap...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2011-03-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368910X514305 |