Legionella metaeffector exploits host proteasome to temporally regulate cognate effector.

Pathogen-associated secretion systems translocate numerous effector proteins into eukaryotic host cells to coordinate cellular processes important for infection. Spatiotemporal regulation is therefore important for modulating distinct activities of effectors at different stages of infection. Here we...

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Bibliographic Details
Main Authors: Tomoko Kubori, Naoaki Shinzawa, Hirotaka Kanuka, Hiroki Nagai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2996335?pdf=render