N-Aryl-7-hydroxy-5-oxo-2,3-dihydro-1H,5H-pyrido-[3,2,1-ij]quinoline-6-carboxamides. The Synthesis and Effects on Urinary Output

N-Aryl-7-hydroxy-5-oxo-2,3-dihydro-1H,5H-pyrido-[3,2,1-ij]quinoline-6-carboxamides. The Synthesis and Effects on Urinary Output

Continuing a targeted search for new leading structures with diuretic action among tricyclic derivatives of hydroxyquinolines, which are of interest as potential inhibitors of aldosterone synthase, the synthesis of a series of the corresponding pyrido[3,2,1-ij]quinoline-6-carboxanilides was carried...

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Bibliographic Details
Main Authors: Igor V. Ukrainets, Lyudmila V. Sidorenko, Mykola Y. Golik, Igor M. Chernenok, Lina A. Grinevich, Alexandra A. Davidenko
Format: Article
Language:English
Published: Österreichische Apotheker-Verlagsgesellschaft m. b. H. 2018-04-01
Series:Scientia Pharmaceutica
Subjects:
anilines
4-hydroxyquinolin-2(1H)-ones
N-aryl-7-hydroxy-5-oxo-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-6-carboxamides
pyridoquinolines
amidation
diuretic activity
Online Access:http://www.mdpi.com/2218-0532/86/2/12

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http://www.mdpi.com/2218-0532/86/2/12

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