Plant virus particles carrying tumour antigen activate TLR7 and Induce high levels of protective antibody.

Plant virus particles carrying tumour antigen activate TLR7 and Induce high levels of protective antibody.

Induction of potent antibody is the goal of many vaccines targeted against infections or cancer. Modern vaccine designs that use virus-like particles (VLP) have shown efficacy for prophylactic vaccination against virus-associated cancer in the clinic. Here we used plant viral particles (PVP), which...

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Bibliographic Details
Main Authors: Jantipa Jobsri, Alex Allen, Deepa Rajagopal, Michael Shipton, Kostya Kanyuka, George P Lomonossoff, Christian Ottensmeier, Sandra S Diebold, Freda K Stevenson, Natalia Savelyeva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4332868?pdf=render

Internet

http://europepmc.org/articles/PMC4332868?pdf=render

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