Synthesis of “Click BOX” ligands and preliminary results on their application in the asymmetric copper catalysed Henry reaction of o-methoxybenzaldehyde

Two new chiral “click BOX” ligands have been synthetised with high yields starting from commercially available dimethyl propargylmalonate and optically pure alkanolamines, followed by copper catalysed cycloaddition (CuAAC) and oxazoline ring formation. Catalytic activity of the new ligands has been...

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Bibliographic Details
Main Authors: Daniela Giunta, PhD, Antonio Arras, Paola Peluso, Maurizio Solinas
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715621000278