The mitochondrial respiratory complex I is a target for 15-deoxy-Δ12,14-prostaglandin J2 action

The prostaglandin J2 derivative 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) is a very active compound with important effects on inflammation, apoptosis, and cell growth processes. To exert this broad range of effects, 15d-PGJ2 binds and alters the activity of diverse proteins, which consequently are...

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Bibliographic Details
Main Authors: B. Martínez, A. Pérez-Castillo, A. Santos
Format: Article
Language:English
Published: Elsevier 2005-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520340086