Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy

Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy

Nilotinib, a tyrosine kinase inhibitor, has been studied extensively in various tumor models; however, no information exists about the pharmacological action of nilotinib in bacterial infections. <i>Mycobacterium bovis</i> (<i>M. bovis</i>) and <i>Mycobacterium avium<...

Full description

Bibliographic Details
Main Authors: Tariq Hussain, Deming Zhao, Syed Zahid Ali Shah, Naveed Sabir, Jie Wang, Yi Liao, Yinjuan Song, Haodi Dong, Mazhar Hussain Mangi, Jiamin Ni, Lifeng Yang, Xiangmei Zhou
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
nilotinib
<i>Mycobacterium bovis</i> (<i>M. bovis</i>)
<i>Mycobacterium avium</i> subspecies <i>paratuberculosis</i> (MAP)
macrophage
autophagy
Online Access:https://www.mdpi.com/2073-4409/8/5/506

Internet

https://www.mdpi.com/2073-4409/8/5/506

Similar Items