The disruption of proteostasis in neurodegenerative disorders

Cells count on surveillance systems to monitor and protect the cellular proteome which, besides being highly heterogeneous, is constantly being challenged by intrinsic and environmental factors. In this context, the proteostasis network (PN) is essential to achieve a stable and functional proteome....

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Bibliographic Details
Main Authors: Ana Jalles, Patrícia Maciel
Format: Article
Language:English
Published: AIMS Press 2015-06-01
Series:AIMS Molecular Science
Subjects:
Online Access:http://www.aimspress.com/Molecular/article/311/fulltext.html