Genomic relationships and speciation times of human, chimpanzee, and gorilla inferred from a coalescent hidden Markov model.

The genealogical relationship of human, chimpanzee, and gorilla varies along the genome. We develop a hidden Markov model (HMM) that incorporates this variation and relate the model parameters to population genetics quantities such as speciation times and ancestral population sizes. Our HMM is an an...

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Bibliographic Details
Main Authors: Asger Hobolth, Ole F Christensen, Thomas Mailund, Mikkel H Schierup
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1802818?pdf=render