New orally active artemisinin dimer antimalarials

Objective: To synthesize orally bioavailable artemisinin dimers and the evaluation of their in vivo antimalarial activity. Methods: Artemsisin dimers were synthesized and their antimalarial activity was determined in in vitro and in vivo studies (administered orally and IP). Results: Dimers 5 and 6...

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Bibliographic Details
Main Authors: Mahmoud A ElSohly, Waseem Gul, Shabana I Khan, Babu L Tekwani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:World Journal of Traditional Chinese Medicine
Subjects:
Online Access:http://www.wjtcm.net/article.asp?issn=2311-8571;year=2017;volume=3;issue=3;spage=1;epage=11;aulast=ElSohly