Siglec-7 Mediates Immunomodulation by Colorectal Cancer-Associated Fusobacterium nucleatum ssp. animalis

Siglec-7 Mediates Immunomodulation by Colorectal Cancer-Associated Fusobacterium nucleatum ssp. animalis

Fusobacterium nucleatum is involved in the development of colorectal cancer (CRC) through innate immune cell modulation. However, the receptors of the interaction between F. nucleatum ssp. and immune cells remain largely undetermined. Here, we showed that F. nucleatum ssp. animalis interacts with Si...

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Bibliographic Details
Main Authors: Dimitra Lamprinaki, Pilar Garcia-Vello, Roberta Marchetti, Charlotte Hellmich, Kelli A. McCord, Kristian M. Bowles, Matthew S. Macauley, Alba Silipo, Cristina De Castro, Paul R. Crocker, Nathalie Juge
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
Fusobacterium nucleatum
colorectal cancer
Siglec-7
outer membrane vesicle
innate immunity
lipopolysaccharide
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.744184/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.744184/full

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