A Key GWAS-Identified Genetic Variant Contributes to Hyperlipidemia by Upregulating miR-320a

A Key GWAS-Identified Genetic Variant Contributes to Hyperlipidemia by Upregulating miR-320a

Summary: It has been unclear whether the elevated levels of the circulating miR-320a in patients with coronary artery disease is due to environmental influence or genetic basis. By recombinant adeno-associated virus (rAAV)-mediated loss- and gain-of-function studies in the mouse liver, we revealed t...

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Bibliographic Details
Main Authors: Zhongwei Yin, Yanru Zhao, Hengzhi Du, Xiang Nie, Huaping Li, Jiahui Fan, Mengying He, Beibei Dai, Xudong Zhang, Shuai Yuan, Zheng Wen, Chen Chen, Dao Wen Wang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Human Metabolism
Genetics
Genomic
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220309858

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http://www.sciencedirect.com/science/article/pii/S2589004220309858

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