A Key GWAS-Identified Genetic Variant Contributes to Hyperlipidemia by Upregulating miR-320a
Summary: It has been unclear whether the elevated levels of the circulating miR-320a in patients with coronary artery disease is due to environmental influence or genetic basis. By recombinant adeno-associated virus (rAAV)-mediated loss- and gain-of-function studies in the mouse liver, we revealed t...
Main Authors: | Zhongwei Yin, Yanru Zhao, Hengzhi Du, Xiang Nie, Huaping Li, Jiahui Fan, Mengying He, Beibei Dai, Xudong Zhang, Shuai Yuan, Zheng Wen, Chen Chen, Dao Wen Wang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-12-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004220309858 |
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