Reduced protocadherin17 expression in leukemia stem cells: the clinical and biological effect in acute myeloid leukemia

Reduced protocadherin17 expression in leukemia stem cells: the clinical and biological effect in acute myeloid leukemia

Abstract Background Leukemia stem cell (LSC)-enriched genes have been shown to be highly prognostic in acute myeloid leukemia (AML). However, the prognostic value of tumor suppressor genes (TSGs) that are repressed early in LSC remains largely unknown. Methods We compared the public available expres...

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Bibliographic Details
Main Authors: Zi-jun Xu, Ji-chun Ma, Jing-dong Zhou, Xiang-mei Wen, Dong-ming Yao, Wei Zhang, Run-bi Ji, De-hong Wu, Li-juan Tang, Zhao-qun Deng, Jun Qian, Jiang Lin
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Translational Medicine
Subjects:
Protocadherin17
Acute myeloid leukemia
DNA methylation
Gene expression
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12967-019-1851-1

Internet

http://link.springer.com/article/10.1186/s12967-019-1851-1

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