Primary Sjögren’s Syndrome of Early and Late Onset: Distinct Clinical Phenotypes and Lymphoma Development

Primary Sjögren’s Syndrome of Early and Late Onset: Distinct Clinical Phenotypes and Lymphoma Development

ObjectivesTo study the clinical, serological and histologic features of primary Sjögren’s syndrome (pSS) patients with early (young ≤35 years) or late (old ≥65 years) onset and to explore the differential effect on lymphoma development.MethodsFrom a multicentre study population of 1997 consecutive p...

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Main Authors: Andreas V. Goules, Ourania D. Argyropoulou, Vasileios C. Pezoulas, Loukas Chatzis, Elena Critselis, Saviana Gandolfo, Francesco Ferro, Marco Binutti, Valentina Donati, Sara Zandonella Callegher, Aliki Venetsanopoulou, Evangelia Zampeli, Maria Mavrommati, Paraskevi V. Voulgari, Themis Exarchos, Clio P. Mavragani, Chiara Baldini, Fotini N. Skopouli, Dimitrios I. Fotiadis, Salvatore De Vita, Haralampos M. Moutsopoulos, Athanasios G. Tzioufas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
primary Sjögren’s syndrome
data driven analysis
age group
lymphoma
clinical phenotype characteristics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.594096/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.594096/full

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