CXCL17-derived CD11b+Gr-1+ myeloid-derived suppressor cells contribute to lung metastasis of breast cancer through platelet-derived growth factor-BB

CXCL17-derived CD11b+Gr-1+ myeloid-derived suppressor cells contribute to lung metastasis of breast cancer through platelet-derived growth factor-BB

Abstract Background Metastasis is the major cause of death from breast cancer. Colonization and adaption of metastatic cells in distant organs is a rate-limiting step of the cancer spreading. The underlying mechanisms responsible for the colonization of breast cancer to lung metastatic niches are no...

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Bibliographic Details
Main Authors: Ya-Ling Hsu, Meng-Chi Yen, Wei-An Chang, Pei-Hsun Tsai, Yi-Chung Pan, Ssu-Hui Liao, Po-Lin Kuo
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Breast Cancer Research
Subjects:
Breast cancer
CXCL17
Lung metastasis
Myeloid-derived suppressor cells
PDGF-BB
Online Access:http://link.springer.com/article/10.1186/s13058-019-1114-3

Internet

http://link.springer.com/article/10.1186/s13058-019-1114-3

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