The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin.

The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin.

Clostridium perfringens ε-toxin (ETX) is a potent pore-forming toxin responsible for a central nervous system (CNS) disease in ruminant animals with characteristics of blood-brain barrier (BBB) dysfunction and white matter injury. ETX has been proposed as a potential causative agent for Multiple Scl...

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Bibliographic Details
Main Authors: Kareem Rashid Rumah, Yinghua Ma, Jennifer R Linden, Myat Lin Oo, Josef Anrather, Nicole Schaeren-Wiemers, Miguel A Alonso, Vincent A Fischetti, Mark S McClain, Timothy Vartanian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004896

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https://doi.org/10.1371/journal.ppat.1004896

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