<i>CDH1</i> Mutation Distribution and Type Suggests Genetic Differences between the Etiology of Orofacial Clefting and Gastric Cancer

<i>CDH1</i> Mutation Distribution and Type Suggests Genetic Differences between the Etiology of Orofacial Clefting and Gastric Cancer

Pathogenic variants in <i>CDH1</i>, encoding epithelial cadherin (E-cadherin), have been implicated in hereditary diffuse gastric cancer (HDGC), lobular breast cancer, and both syndromic and non-syndromic cleft lip/palate (CL/P). Despite the large number of <i>CDH1</i> mutati...

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Bibliographic Details
Main Authors: Arthavan Selvanathan, Cheng Yee Nixon, Ying Zhu, Luigi Scietti, Federico Forneris, Lina M. Moreno Uribe, Andrew C. Lidral, Peter A. Jezewski, John B. Mulliken, Jeffrey C. Murray, Michael F. Buckley, Timothy C. Cox, Tony Roscioli
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Genes
Subjects:
orofacial clefting
cleft lip
cleft palate
gastric cancer
cadherin 1
genotype-phenotype correlation
Online Access:https://www.mdpi.com/2073-4425/11/4/391

Internet

https://www.mdpi.com/2073-4425/11/4/391

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