Novel Sustained-Release Drug Delivery System for Dry Eye Therapy by Rebamipide Nanoparticles

The commercially available rebamipide ophthalmic suspension (CA-REB) was approved for clinical use in patients with dry eye; however, the residence time on the ocular surface for the traditional formulations is short, since the drug is removed from the ocular surface through the nasolacrimal duct. I...

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Bibliographic Details
Main Authors: Noriaki Nagai, Miyu Ishii, Ryotaro Seiriki, Fumihiko Ogata, Hiroko Otake, Yosuke Nakazawa, Norio Okamoto, Kazutaka Kanai, Naohito Kawasaki
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/2/155