CAIX Regulates GBM Motility and TAM Adhesion and Polarization through EGFR/STAT3 under Hypoxic Conditions

CAIX Regulates GBM Motility and TAM Adhesion and Polarization through EGFR/STAT3 under Hypoxic Conditions

Carbonic anhydrases (CAs) are acid–base regulatory proteins that modulate a variety of physiological functions. Recent findings have shown that CAIX is particularly upregulated in glioblastoma multiforme (GBM) and is associated with a poor patient outcome and survival rate. An analysis of the GSE429...

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Bibliographic Details
Main Authors: Bor-Ren Huang, Yu-Shu Liu, Sheng-Wei Lai, Hui-Jung Lin, Ching-Kai Shen, Liang-Yo Yang, Dah-Yuu Lu
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
CAIX
hypoxic condition
GBM
motility
M2 polarization
Online Access:https://www.mdpi.com/1422-0067/21/16/5838

Internet

https://www.mdpi.com/1422-0067/21/16/5838

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