Inhibition of dengue virus entry and multiplication into monocytes using RNA interference.

BACKGROUND: Dengue infection ranks as one of the most significant viral diseases of the globe. Currently, there is no specific vaccine or antiviral therapy for prevention or treatment. Monocytes/macrophages are the principal target cells for dengue virus and are responsible for disseminating the vir...

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Bibliographic Details
Main Authors: Mohammed Abdelfatah Alhoot, Seok Mui Wang, Shamala Devi Sekaran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3226553?pdf=render