Synergistic Effect of 1,3,6-Trihydroxy-4,5,7-Trichloroxanthone in Combination with Doxorubicin on B-Cell Lymphoma Cells and Its Mechanism of Action Through Molecular Docking

Synergistic Effect of 1,3,6-Trihydroxy-4,5,7-Trichloroxanthone in Combination with Doxorubicin on B-Cell Lymphoma Cells and Its Mechanism of Action Through Molecular Docking

ABSTRACT: Background: The increasing rate of cancer chemoresistance and adverse side effects of therapy have led to the wide use of various chemotherapeutic combinations in cancer management, including lymphoid malignancy. Objective: We investigated the effects of a combination of 1,3,6-trihydroxy-...

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Bibliographic Details
Main Authors: Isnatin Miladiyah, Dr, Emmy Yuanita, Dr, Satyo Nuryadi, MEng, Jumina Jumina, PhD, Sofia Mubarika Haryana, PhD, Mustofa Mustofa, Dr
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Current Therapeutic Research
Subjects:
c-Jun N-terminal kinase
Doxorubicin sensitivity
Lymphoma
Raf-1
Synergistic
Xanthone synthetic
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X20300023

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http://www.sciencedirect.com/science/article/pii/S0011393X20300023

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