Targeted Therapy with Sirolimus and Nivolumab in a Child with Refractory Multifocal Anaplastic Ependymoma

Targeted Therapy with Sirolimus and Nivolumab in a Child with Refractory Multifocal Anaplastic Ependymoma

Pediatric ependymoma (EPN) is the third most common central nervous system (CNS) tumor, with 90% arising intracranially. Management typically involves maximal surgical resection and radiotherapy, but patients’ outcome is poor. Moreover, there are only a few therapeutical options available for recurr...

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Bibliographic Details
Main Authors: Katia Perruccio, Angela Mastronuzzi, Marco Lupattelli, Francesco Arcioni, Ilaria Capolsini, Carla Cerri, Grazia M. I. Gurdo, Maria Speranza Massei, Elena Mastrodicasa, Maurizio Caniglia
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Reports
Subjects:
pediatric
brain tumors
immune checkpoint inhibitor
Online Access:https://www.mdpi.com/2571-841X/4/2/12

Internet

https://www.mdpi.com/2571-841X/4/2/12

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