Computational comparison of common event-based differential splicing tools: practical considerations for laboratory researchers

Computational comparison of common event-based differential splicing tools: practical considerations for laboratory researchers

Abstract Background Computational tools analyzing RNA-sequencing data have boosted alternative splicing research by identifying and assessing differentially spliced genes. However, common alternative splicing analysis tools differ substantially in their statistical analyses and general performance....

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Bibliographic Details
Main Authors: Ittai B. Muller, Stijn Meijers, Peter Kampstra, Steven van Dijk, Michel van Elswijk, Marry Lin, Anna M. Wojtuszkiewicz, Gerrit Jansen, Robert de Jonge, Jacqueline Cloos
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Bioinformatics
Subjects:
Alternative splicing
RNA-sequencing
Computational performance
Online Access:https://doi.org/10.1186/s12859-021-04263-9

Internet

https://doi.org/10.1186/s12859-021-04263-9

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